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 TUBE GRANULOMA  
TUBE GRANULOMA:
INTRODUCTION 5
HISTOPATHOLOGICAL FEATURES

TUBE GRANULOMA:
INTRODUCTION 5
HISTOPATHOLOGICAL FEATURES

Description : Histologically, tube granulomas combine the features of acute inflammatory granulation tissue (numerous newly formed capillaries and an inflammatory polymorphonuclear leukocyte infiltration within a loose, areola fibrous tissue stroma) and the features of a keratin foreign body granuloma.

The key to the histologic diagnosis of keratin foreign-body granuloma is the presence of keratin squames within otherwise empty and irregularly shaped slit-like spaces which are surrounded by foreign-body giant cells. The keratin squames can be identified by their shape, size, strong eosinophilic staining, and by birefringence under polarized light.

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